What is an eCOA clinical trial?

An eCOA clinical trial uses technology to accelerate clinical data collection and ensure proper data quality analyses. More sponsors are choosing eCOA for their clinical trials to gain a better understanding of how patients feel and function in near real-time.

What is the difference between eCOA and ePRO

The difference between Electronic Clinical Outcome Assessment (eCOA) and Electronic Patient-Reported Outcome (ePRO) is that ePRO systems are a type of eCOA. Clinical trial patients often use eCOA system technologies on mobile devices to remotely send their ePRO symptoms and experience directly to site staff. Other types of COA include Electronic Performance Outcome ePerfO, Electronic Clinician-Reported Outcome (eClinRO), and Electronic Observer-Reported Outcome (eObsRO).

Does Signant have an instrument library?

Signant's instrument library contains over 50 instruments commonly used in clinical trials. In many cases, we offer pre-approved versions, which means an author review step is not required. Additionally, our library instruments are designed using best practices and are pre-validated, so they do not require additional testing when implemented in a new clinical study, saving you time and ensuring high quality.

Can you provide scientific consulting to support our eCOA approach?

Signant proudly provides expert consulting with our solutions, like eCOA. We believe that combining our advanced technology with scientific and clinical expertise properly sets studies up for success. Our focus on protecting data quality along with our credibility among authors and license holders helps us successfully navigate electronic implementations. With a deep understanding of regulatory needs, our team can help steer clients throughout their clinical trials.

Can Signant implement computerized adaptive tests (CATs)?

Yes. Signant SmartSignals eCOA includes the ability to implement the PROMIS CAT seamlessly alongside conventional PROMS. Choose from more than 20 domains including anxiety, depression, fatigue, sleep disturbance, pain interference, physical function, and social function. For more information, read our PROMIS CAT brochure and white paper.

Signant Clinical Trials Solution

SOLUTION

Great technology with full-featured, best-in-class solutions and no capability gaps. From eCOA and EDC to RTSM and supply chain management.

SCIENCE

Unrivalled scientific and technical expertise ensuring trial and data integrity from protocol design to study completion.

SERVICE

Attentive, experienced support with high-quality, mature project management. Every customer receives dedicated attention with 24/7 multilingual helpdesk.

SCALE

Global infrastructure for today's trials with architectural and operational capacity supporting complex, multinational studies.

We provide comprehensive eClinical technology solutions including eCOA, EDC, RTSM, and supply chain management, backed by 25+ years of scientific and regulatory expertise.

We support all major therapeutic areas including oncology, CNS, rare disease, and cardiovascular studies with specialized expertise for each area's unique requirements.

Contact our team for a consultation about your specific study requirements. We'll connect you with the right solution experts and provide protocol-specific guidance.

Signant Health is the evidence generation company. We are focused on leveraging software, deep therapeutic and scientific knowledge, and operational expertise to consistently capture, aggregate, and reveal quality evidence for clinical studies across traditional, virtual, and hybrid trial models. For more than 25 years, over 600 sponsors and CROs of all sizes – including all Top 20 pharma – have trusted Signant solutions for remote and site-based eCOA, EDC, eConsent, RTSM, supply chain management, and data quality analytics.
Learn more at www.signanthealth.com.

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