Endpoint Confidence Built In from the Start

Rater Station® embeds scientific expertise in the platform itself, standardizing how CNS scales are administered, scored, and reviewed to protect endpoint reliability.

DISCUSS YOUR PROTOCOL

The Measurement Challenge

ClinRO measures in CNS trials are complex instruments. Quality endpoint data depends on consistent administration, accurate scoring, and correct patient eligibility, enforced across every site and every rater. Rater Station® is built to safeguard endpoint reliability by design.

Science Encoded in the Technology

This is proven technology, trusted by leading global pharmaceutical companies. 

Structured workflows

Rater Station® guides administration of the full range of CNS scales through structured workflows, with automated scoring validation and scientifically informed edit checks that monitor internal consistency based on the clinical logic built into each scale.

Eligibility verification

Eligibility verification with automatic alerts prevents inappropriate patient inclusion.

Integrated A/V recording

Integrated A/V recording of interviews enables seamless expert central review of scale administration and scoring quality to drive continued endpoint quality throughout each trial.

Automated rater gating

The software implements automated rater gating to ensure only certified raters conduct assessments.

What This Means for Your Study

When scientific rigor is encoded in the technology itself, data quality does not rest solely on individual raters. 


Eligibility errors are caught early.

Eligibility errors are caught early.


Scoring inconsistencies surface in real time.

Scoring inconsistencies surface in real time.

A/V recordings and immediate access to clean source data enable timely expert central review.

A/V recordings and immediate access to clean source data enable timely expert central review.

Rater Station maintains quality proactively throughout the entire study lifecycle.

Rater Station maintains quality proactively throughout the entire study lifecycle.

The result for sponsors is confidence in endpoint data, fewer downstream corrections, and a regulatory submission built on quality evidence generation.

A Track Record
That Validates the Approach

The platform has supported regulatory submissions across 70+ CNS indications, including mood disorders, schizophrenia, Alzheimer’s, and novel mechanisms including psychedelics and ketamine. The impact of our rater training services has been documented in peer-reviewed literature, demonstrating measurable improvements in inter- and intra-rater variability.

70+ 

INDICATIONS

70K+ 

PATIENTS

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Let's discuss your protocol

Frequently Asked Questions

How does Rater Station enforce scale administration consistency across sites?
Pre-set scale-specific workflows guide raters through administration with on-screen embedded guidance and automated scoring validation.
What does automated rater gating actually do?
Rater Station automatically restricts scale access until rater qualification requirements are verified. Only raters who have completed and passed training and qualification can conduct study assessments, enforced by the platform itself rather than through manual oversight.
How do eligibility edit checks work?
 Customizable edit checks apply protocol-specific eligibility thresholds with real-time alerts, flagging inclusion errors to ensure correct study populations.
Is the platform used for novel mechanism studies such as psychedelics and ketamine?
Yes. Rater Station has supported studies across psychedelic and ketamine protocols. The same platform capabilities apply: scale-specific workflows, integrated A/V, real-time data, and automated controls.

WHO IS SIGNANT HEALTH


Signant Health is the evidence generation company, leveraging software, deep therapeutic and scientific knowledge, and operational expertise to deliver quality evidence across traditional, virtual, and hybrid trial models. For over 25 years, 600+ sponsors and CROs of all sizes – including all Top 20 pharma – have trusted Signant’s comprehensive eClinical solutions. Our clinical outcome assessments (eCOA, clinician ratings, cognitive testing) and wearable digital health technologies powered by Ametris provide the industry's most comprehensive evidence generation capabilities, alongside EDC, eConsent, RTSM, supply chain management, and data quality analytics. Learn more at www.signanthealth.com.